Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
SEC Sues Two for Insider Trading of Sequenom and Exact Sciences Shares
December 09, 2010
The SEC alleges the two individuals traded shares of the two firms after receiving insider information about Sequenom's unsuccessful bid to acquire Exact Sciences in 2009 and Sequenom's mishandling of data on its Down syndrome test.
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