Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Quest Expanding Point-of-Care Test Portfolio, Presence in Indian Market
During its fourth-quarter earnings call Quest reported revenues increased 14.3 percent to $1.8 from the year-ago period, and profit from continuing operations inched up to $154 million from $151 million.
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