Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Qiagen to Transfer Transplant Dx Rights to Olerup
Qiagen will transfer distribution rights for the Olerup line of molecular transplantation testing products to LinkMed subsidiary Olerup International, but also said that it will increase its focus on higher-growth applications in transplantation testing, such as sequencing-based typing.
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