Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
NY State Regulating DTC Genomics Firms as Labs
Despite claims by DTC genomics firms that they shouldn't be regulated as clinical labs, New York State is doing just that. A state health department official said companies that obtain raw data from an analytical testing facility and send a report to an ordering practitioner are considered laboratories.
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