Regulation and Function of miR-218 in Gastric Cancer Metastasis
Tie, Pan et al., PLoS Genetics
Researchers describe a negative feedback system between Robo1, a Slit receptor, and miR-218, wherein “decreased miR-218 levels eliminate Robo1 repression, which activates the Slit-Robo1 pathway through the interaction between Robo1 and Slit2, thus triggering tumor metastasis.” The authors suggest that the restoration of miR-218 supresses Robo1 espression and inhibits tumor cell invasion.
Navigenics Agrees Not to Market Genetic Testing Services Directly to NY Residents
In order to operate in New York, "Navigenics agreed to make certain concessions … by modifying the DTC portion of their business," a regulatory official from the NY Department of Health's Wardsworth Center said this week.
New to GenomeWeb? Register quickly here.
