Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Myriad Prepared to Make Small IP Sacrifice to Aussies in Light of Landmark US Patent Case
October 06, 2010
In deciding to surrender a key patent to the Australian government, it seems Myriad may be preparing to sacrifice a small slice of its IP holdings in a secondary market in an effort to avoid any erosion of its position in the landmark US case challenging seven of its BRCA gene patents.
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