Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Lawrence Corey Named New President and Director of FHCRC
As the successor to Lee Hartwell at the Fred Hutchinson Cancer Research Center, Lawrence Corey said that he would work to expand both basic and clinical research; enhance survival and prevention of cancer and other diseases; improve healthcare to individuals and the entire population; and strengthen existing faculty mentoring programs.
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