Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
LabCorp Extends Offer for Monogram; Aims to Settle with Shareholders
The $107 million offer was extended to allow for the public disclosure of amendments to the offering that reflect an agreement in principle to settle a class action shareholder suit.
New to GenomeWeb? Register quickly here for free access.