Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Iverson Begins CMS-Funded Warfarin PGx Study; Plans to Return Test Results Within 24 Hours
March 09, 2011
While past studies that have attempted to gauge the clinical utility of warfarin PGx testing have been hampered by slow test turnaround times, Iverson is promising to provide genetic test results within 24 hours.
Full-text access for premium subscribers only.
Existing premium subscribers login here.
New to GenomeWeb? Register quickly here.
New to GenomeWeb? Register quickly here.
Related Stories
- FDA Rejects Avastin as Breast Cancer Drug; Genentech to Conduct New Trial to ID Best Responders
November 30, 2011 / Pharmacogenomics Reporter - Following Merger, Express Scripts May Cut Back Medco's Personalized Medicine Programs
May 9, 2012 / Pharmacogenomics Reporter - Dx Focus: Roche Cobas p 630; Abbott Plex-ID System; Trio of New C. Diff Tests; MDI's MRSA Panel
April 5, 2012 / PCR Insider - FDA Approves Roche's Pre-analytical Tool for Cobas System
March 30, 2012 / GenomeWeb Daily News - Generex to Meet with FDA about AE37 HER2 Peptide Vaccine; Companion Dx Path Still Unclear
March 7, 2012 / Pharmacogenomics Reporter