Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
H1N1 Flu Tests Lose Emergency Use Status from FDA
A number of molecular diagnostic tests that were cleared for emergency use during the 2009 H1N1 influenza pandemic will have to seek full FDA clearance now that HHS has declared the emergency over.
New to GenomeWeb? Register quickly here for free access.