Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
GeneNews Cuts Q1 Loss as It Prepares Test Launch
May 05, 2010
The firm had hardly any revenue for the first quarter, as it gears up for the launch of its ColonSentry test. It was able to cut its net loss significantly, however.
Full-text access for registered users only.
Existing users login here.
New to GenomeWeb? Register quickly here for free access.
New to GenomeWeb? Register quickly here for free access.