Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
CVS Caremark Expands Investment in Generation Health
CVS Caremark is increasing its investment in Generation Health for an undisclosed amount. Additionally, the CEO of the genetic benefits management firm, Per Lofberg, will now take over as president of CVS Caremark's PBM division.
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