Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Continuing Push to Diversify Offerings, Myriad Licenses Chronix's Early Cancer Detection Technology
May 11, 2011
Chronix has yet to complete validation studies for its prostate, breast, and colon early detection cancer tests, so questions remain as to when the license will begin adding to Myriad's revenues.
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