Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
CollabRx Debuts Cancer Genomics Service to Distinguish Itself from DTC Genomics Firms
The web-based CollabRx One program, which will charge cancer patients between $50,000 and $100,000 to generate genetically-targeted treatment options, compares 15,000 genes against tumor samples to gauge how they respond to as many as 5,000 drugs.
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