Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Celera Implementing Restructuring Plan in Response to Revenue Drop
July 23, 2009
Celera announced today that it is implementing a restructuring plan in light of its Q2 2009 revenues, which are expected to be down from its Q2 2008 revenues.
Full-text access for registered users only.
Existing users login here.
New to GenomeWeb? Register quickly here for free access.
New to GenomeWeb? Register quickly here for free access.
Related Stories
- Following Merger, Express Scripts May Cut Back Medco's Personalized Medicine Programs
May 9, 2012 / Pharmacogenomics Reporter - Knowledge of KIF6 Mutation Status Increases Patients' Statin Adherence, Medco Study Finds
March 28, 2012 / Pharmacogenomics Reporter - UPCI Team Developing Lung Cancer Dx; Latest Entrant into Crowded, Growing Space
March 23, 2012 / ProteoMonitor - Integrated Diagnostics Secures Additional $10M to Prep for 2013 Launch of Lung Cancer Dx
February 24, 2012 / ProteoMonitor - Medco Study Suggests Genetic Testing Improves Patient Compliance with Statins
October 19, 2011 / Pharmacogenomics Reporter