Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
California Legislation Seeks to Bar UC Berkeley's Genetic Testing Plans
"We have provided answers to an array of specific questions posed by committee staff who are working on AB 70," Mark Schlissel, UC Berkeley's dean of biological sciences, told Pharmacogenomics Reporter this week. "Personally, I do not believe that the State Legislature should be considering bills that would dictate aspects of the curriculum at its university system."
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