Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Affymetrix Transfers Ownership of CLIA Lab to Navigenics
Affy has decided to refocus its efforts on its core microarray platform and being an enabler for the broad adoption of microarrays across all genetic analysis markets, including CLIA lab services. Meanwhile, Navigenics takes over ownership of the lab as the volume of orders for its genetic screening service has increased.
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