Family-Based Whole-Genome Sequencing Reveals Candidates for Mendelian Disease
Roach, Glusman et al., Science
Researchers at the Institute for Systems Biology and Complete Genomics have identified candidate disease-causing genes for Miller syndrome and ciliary dyskinesia, both Mendelian disorders. They sequenced the genomes of a family of four, allowing them to determine recombination sites with precision (at 99.999 percent accuracy) and identify rare single-nucleotide polymorphisms. "Our results demonstrate the unique value of complete genome sequencing in families," the authors write.
Cryo-Cell Inks Distribution, Research Pacts with S-Evans for MenSC Tech
China's SEB will exclusively market and sell Cryo-Cell's menstrual stem cell service throughout Thailand, and the companies will study global gene expression and conduct pre-clinical studies of type 1 diabetes using Cryo-Cell's MenSC's.
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