Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Celera's Q4 Revenues Increase 15 Percent; Swings to Loss
February 18, 2009
Celera's revenues were driven by sales of its KIF6 testing service, but the firm posted a loss for the second quarter in a row on higher SG&A spending related to building its infrastructure following its split from Applera.
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