Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Caliper, Illumina Stocks Lead 2010 GWDN Index
January 04, 2011
The stock prices of both Caliper Life Sciences and Illumina increased more than 100 percent in 2010, while Vermillion and CombiMatrix led the decliners. Overall, the GWDN Index increased 16 percent, keeping pace with the broader market rebound.
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