Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
What Do You Mean, Alternative?
Steven Salzberg blogs on the recent creation by the NIH of the National Center for Complementary and Alternative Medicine. Determining Ayurvedic medicine, just one area that the NCCAM will fund, to be a form of quackery, Salzberg discredits the NIH for doling out money to what he considers inferior projects when those funds could be going toward more traditional research. Read his opinion here.