Chromosome-Scale Selective Sweeps and Genomic Diversity in C. elegans
Andersen, Gerke et al., Nature Genetics
Researchers at Princeton University and elsewhere discuss the effects of chromosome-scale selective sweeps on genomic diversity in Caenorhabditis elegans. Taking a high-throughput selective sequencing approach on a collection of 200 wild C. elegans strains, the team found that the nematode's "genome variation is dominated by a set of commonly shared haplotypes on four of its six chromosomes, each spanning many megabases." Further, the team reports on its population genetic modeling experiments, which showed that "this pattern was generated by chromosome-scale selective sweeps that have reduced variation worldwide; at least one of these sweeps probably occurred in the last few hundred years," it writes.
Tennessee Clinical Lab Remains Committed to Joining New Knoxville Bio Park
Molecular Pathology Laboratory Network, a Tennessee diagnostic lab that performs tests for clients nationwide, remains committed to building a new headquarters in a new tech park in Knoxville, according to its president.
However, it could be years before the Maryville-based lab, which specializes in oncology and women's health testing, breaks ground on any new buildings in the so-called Pellissippi Place park. MPLN President Roger Hubbard said he is waiting for the economy to improve before investing in new facilities.
"It's no secret the economy has hurt a lot of businesses," Hubbard told Knoxsvillebiz.com earlier this month. "But there are positive signs the economy is turning around. We are picking up momentum and we are going to be in here."
According to the news site, the park is being funded by a multi-jurisdictional partnership comprising Knox and Blount counties in Tennessee, and the cities of Alcoa and Maryville, each of which has invested $5 million.
The federal government allocated $2 million in the project.
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