Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
SC 09 Focuses on Bio-Computing
By Matthew Dublin
Super Computing 09 has just released an announcement that shows they're making good on this year's bio-computing thrust area. According to the release, the Department of Energy's Genomic Science Program will be hosting a workshop called "Using Clouds for Parallel Computations in Systems Biology" which will explore on-demand access to computing resources and systems biology applications. So far, presenters at the Bio-Computing thrust area will include the following: