Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Picturing a PhD
Matthew Might, an assistant professor at the University of Utah, says he has a difficult time explaining "what a PhD is" to incoming doctoral candidates, because it's "hard to describe it in words." Naturally, he uses pictures, as he explains at his blog. Check out Might's pictorial representation of a doctorate degree, here.
HT: Bayblab and Samantha Scientist