Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
A New One Steps In
April 08, 2009
On its blog, Navigenics has announced that its new president and CEO will be Jonathan Lord. Previously, Lord was the chief innovation officer at Humana in Louisville, and before that he was president of Boston's Health Dialog. Lord replaces Mari Baker, who headed to Playfirst, an entertainment and video game company, in March. Lord will start on the first of May.