Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
More Jobs
February 06, 2012
The healthcare sector in the US added just more than 30,000 jobs last month, reports The Wall Street Journal's Health Blog. The overall economy added 243,000 jobs. However, the blog notes that the data from the Bureau of Labor Statistics breaks the numbers down by facility type, not job description. "For example, the report shows that hospitals added 12,700 jobs, but doesn't say whether those were nursing, IT, or cafeteria positions," it says.