The Drosophila melanogaster Genetic Reference Panel
Mackay, Richards et al., Nature
North Carolina State University's Trudy Mackay and her colleagues present the Drosophila melanogaster Genetic Reference Panel, "a community resource for analysis of population genomics and quantitative traits."
Lee Hood Promotes P4 at AACC
July 30, 2010
During the final plenary session at the 2010 annual meeting of the American Association for Clinical Chemistry, Leroy Hood spoke of "transforming healthcare" via the P4 "revolution," encompassing a predictive, personalized, preventive, and participatory approach to health and disease — a "paradigm shift" that he says will produce "enormous economic opportunities" with "dramatically lower[ed] health care costs." Hood discussed the commitment at Institute for Systems Biology and other institutions – notably the Ohio State University College of Medicine, co-founder of the P4 Medicine Institute, along with the ISB – to next-generation genomic, proteomic, transcriptomic, and microfluidic technologies, as well as integrative computational methods.
Blood-based diagnostics, he told meeting attendees, "will be the key to P4 medicine." Hood envisions that in the next 10 years, physicians will adopt a "systems approach to disease," whole-genome sequencing will be performed in the familial context, and patient-specific assays will be used biannually and will interrogate 2,500 proteins in order to quantify "wellness."
Hood also spoke of his intent to establish, in Seattle, "a very large facility to be able to accumulate human genome sequences as they become available, with phenotypes and adequate records," so that investigators can mine the data for "the collective mining that will create the predictive medicine of the future.
I cannot agree more. For
I cannot agree more.
For years I am "lobbying" for physicians to adopt a "systems approach to disease," whole-genome sequencing to be performed in the familial context, and patient-specific assays, using the words of Lee Hood.
The way to go is:" with phenotypes and adequate records," so that investigators can mine the data for "the collective mining that will create the predictive medicine of the future".
Emanuel Yakobson, Ph.D.
Rehovot, Israel
Oxford, UK
I cannot agree more. For
I cannot agree more.
For years I am "lobbying" for physicians to adopt a "systems approach to disease," whole-genome sequencing to be performed in the familial context, and patient-specific assays, using the words of Lee Hood.
The way to go is:" with phenotypes and adequate records," so that investigators can mine the data for "the collective mining that will create the predictive medicine of the future".
Emanuel Yakobson, Ph.D.
Rehovot, Israel
Oxford, UK