KCTD13 a Driver of Neurodevelopmental Phenotypes Associated with the 16p11.2 CNV
Golzio, Willer et al., Nature
An international team led by investigators at Duke University shows that KCTD13 "is a major driver for the neurodevelopmental phenotypes associated with the 16p11.2 CNV [copy-number variant]," a finding that it says substantiates "the idea that one or a small number of transcripts within a CNV can underpin clinical phenotypes, and offer an efficient route to identifying dosage-sensitive loci."
But Is It a "Google-Killer"?
Wolfram Alpha launched on Monday and tech-loving people have taken the time this week to check it out. Prior to the launch, CNET wrote about the hardware that the "computational knowledge engine" is built on, namely a system made by R Systems from Dell hardware, called R Smarr, that can perform 39.6 trillion mathematical operations per second. After the launch, CNET's Matt Asay didn't seem too impressed, saying that "the best software strategies are those that encourage outside contributions, rather than discourage it." Omics Omics' Keith Robison says he is "underwhelmed." Robison puts the engine through its paces, searching for trains between New York and Chicago, for the KRAS gene, for panda taxonomy, and more and he concludes, "I've thrown a bunch of queries at it, and have yet to find something really cool." The Financial Times' tech blog is similarly unimpressed, adding that "Google has nothing to be worried about."
Yep.. I checked it, I guess
Yep.. I checked it, I guess Wolfram should have spent more time in alpha version before coming out in open for critics to shread it apart.
Hopefully Wolfram will learn from this misstep and come out stronger.
Which is what I thought
Which is what I thought also.
http://www.hpcprogrammer.com/?p=55
Think of it as an online version of Mathematica + Dictionary.
They tried too hard to be first in the semantic web race and tried to define what it should be. But as they say in show biz -- There is not such thing as bad press... -- except of course in IT.
Considering his humongous
Considering his humongous tome based solely on the brilliant insight that simple rules can lead to complex results (else chess would be easy, eh?), Wolfram should consider resting on his Mathematica laurels.