Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Genoptix Becomes Member of Aetna's National Provider Network
Genoptix today said Aetna has tapped it to offer specialized lab and comprehensive diagnostic services for hematomalignancies as part of its national provider network.
The three-year agreement will begin April 1. Aetna which covers 19 million lives in the US.
Additional terms of the deals were not disclosed.