Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
The Future of Supercomputing Software Libraries
February 16, 2012
In this video, D.K. Panda from Ohio State University presents his talk on the future of supercomputers software libraries. The video was recorded on Feb 7th at the recent HPC Advisory Council Israel Supercomputing Conference.
In the video, Panda discusses the emergence of exaflop-scale computing, trends in commodity computing clusters, and the challenges associated with scaling software to billions of processors to meet the demands of exascale computing.