Family-Based Whole-Genome Sequencing Reveals Candidates for Mendelian Disease
Roach, Glusman et al., Science
Researchers at the Institute for Systems Biology and Complete Genomics have identified candidate disease-causing genes for Miller syndrome and ciliary dyskinesia, both Mendelian disorders. They sequenced the genomes of a family of four, allowing them to determine recombination sites with precision (at 99.999 percent accuracy) and identify rare single-nucleotide polymorphisms. "Our results demonstrate the unique value of complete genome sequencing in families," the authors write.
Francis vs. the Atheists: This Won't Be Pretty
April 17, 2008
At Framing Science, Matthew Nisbet uses today's premier of the movie Expelled to caution atheist scientists about going too far. He excerpts a Pew interview with Francis Collins, who breaks down why "the current crowd of seemingly angry atheists, who are using science as part of their argument that faith is irrelevant, do not speak for us," Collins says. He goes on to say that 40 percent of scientists believe in a personal God. "To the extent that it can be made clear that the assault on faith, which has been pretty shrill in the last couple of years, is coming from a fringe — a minority — and is not representative of what most scientists believe, that would help defuse the incendiary rhetoric and perhaps allow a real conversation about creation," he tells Pew.
