Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
DNA Rules in the Courtroom
Governor Spitzer is proposing a bill that would expand the state's DNA criminal database to include DNA taken from anyone found guilty of a misdemenaor. New York is one of only a few states to have such a database in place. The bill could make it easier to both convict the guilty and free the innocent, but it could also push the boundaries of privacy.