Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Keeping the Balance
Tunisia Riley at Under the Microscope compiled a list of family-friendly companies in science, technology and health. She says that each of the companies on her list "have one or more of the following: a high percentage of women employees, good paid maternity/paternity leave, on-site childcare and a proven commitment to a work-life balance for their employees." And that list includes Cornell University, Eli Lily, and Genentech, among others.