Big Data Bummers

Excitement about big data is in fever pitch, but expectations may need tempering.

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Your poll is a bit

Your poll is a bit outdated-we're already seeing a big impact on biomedical research. The problem is that society (politics, insurance, doctors) isn't keeping up with the technology and actually hinders it's advancement.

The biggest impact BIG DATA

The biggest impact BIG DATA is having on biomedical research is diversion of funding in a time when 80% of the data points cannot be duplicated.

Stars do not create darkness, nor does cancer create mutations.

There are large amounts of

There are large amounts of statistically significant findings in 'Big data'. However, translate those findings to benefit for population is a big, big leap. Please see two tables in the paper:
BMC Medical Informatics and Decision Making. 2014, 14:15: Quantification of population benefit in evaluation of biomarkers: practical implications for disease detection and prevention.

Let's hear it for Marcus and

Let's hear it for Marcus and Davis (and Perkins). Garbage in--garbage out. Lots of garbage in--big garbage out. Look no further than the Quackenbush paper ("Inconsistency in large pharmacogenomic
studies" Nature (2013) 504:389) or Ioannidis (Why most published research findings are false." PLoS Med, Aug 2005; 2(8): e124. is good but so are a number of other of his articles)Big data looks impressive but if it arises from questionable sources great care is needed. It is too easy to impress (or baffle) with megadata when there is no meaning behind it.