Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Because Another One Is Needed
May 19, 2009
The Genetic Genealogist Blaine Bettinger writes that Pathway Genomics, a recently-launched DTC genetic testing company, has started to send out test kits. (Bettinger is a consultant for the company.) Pathway offers three options to test ancestry, health, or both, for $199, $249, or $348, respectively.