Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
And Trakr, Too
Trakr, the German shepherd who located the last Sept. 11 survivor in New York, was cloned by BioArts International (of MissyToo fame) after Trakr's owner James Symington, a former Canadian police officer, entered an essay contest. The cloning was led by Hwang Woo-Suk (whose work in cloning dogs has held up) at the Sooam Biotech Research Foundation in South Korea and resulted in five puppies from their surrogate mothers, born between last December and April. Symington says that if the pups have Trakr's abilities, he will train them to also be search-and-rescue dogs. As for Trakr, he died two months ago at the age of 16.