Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Amazon Cuts Cloud Storage Prices
Amazon Web Services have announced their latest price reduction, this time for storage. Amazon S3 standard storage customers will see the most benefit from these price cuts. For example, if you're storing 50 terabytes of data you can expect a 12 percent reduction in cost, or if you have 500 terabytes of data you will now see a 13.5 percent savings in cost.
The following price reductions were made effective February 1, 2012.

These savings are a direct result of the continued growth of S3, which by the end of 2011 hosted roughly 762 billion objects. At peak times, S3 processes 500,000 request pre second. Since 2006, the total number of objects stored on S3 has grown by 192 percent, with last year experiencing the most significant growth.
