Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
AHRQ's Tech-Assessment Program Seeks Comments for CYP2D6, KRAS, BCR-ABL1 Dxs
January 29, 2010
AHRQ's Technology Assessment Program yesterday issued a call for public comment on certain pharmacogenomic lab tests: CYP2D6 for tamoxifen in breast cancer, KRAS for anti-EGFR antibodies in colorectal cancer, and BCR-ABL1 for tyrosine kinase inhibitors in chronic myeloid leukemia.
The comment period runs through Feb. 12.
The Call for Public Review document can be found here.
