Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Upstate NY's Trudeau Institute Taps HRI for Biomedical Tech-Transfer Services
Health Research Incorporated, which is affiliated with the New York State Department of Health and the Roswell Park Cancer Institute, will help the Trudeau Institute establish its first real tech-transfer program to commercialize basic research on immune response to infectious disease.
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