Regulation and Function of miR-218 in Gastric Cancer Metastasis
Tie, Pan et al., PLoS Genetics
Researchers describe a negative feedback system between Robo1, a Slit receptor, and miR-218, wherein “decreased miR-218 levels eliminate Robo1 repression, which activates the Slit-Robo1 pathway through the interaction between Robo1 and Slit2, thus triggering tumor metastasis.” The authors suggest that the restoration of miR-218 supresses Robo1 espression and inhibits tumor cell invasion.
University of Toledo Forms $10M Investment Fund to Bolster Research Commercialization
The fund, which will come from revenues derived from auxiliary services on the UT campus, will likely support federal grant-matching programs and proof-of-concept awards. In particular, UT will use the fund to maximize a recent influx of life sciences research commercialization opportunities that have arisen since it merged with the Medical University of Ohio two years ago.
New to GenomeWeb? Register quickly here for free access.
