Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
OHSU, Spinout Najit, and WUSTL to Co-Develop West Nile Vaccine Using $7.3M NIAID Grant
As owner of the underlying platform technology, Oregon Health and Science University stands to benefit financially if Najit can successfully market a vaccine for West Nile virus or any other infectious disease.
New to GenomeWeb? Register quickly here for free access.