Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Ohio Awards Public-Private Stem-Cell Consortium $5M to Help Market Its Discoveries
The Center for Stem Cell and Regenerative Medicine, which comprises researchers from Ohio academic institutions, research hospitals, and the private sector, will use the grant to fund nine new research projects this year and at least eight in coming years.
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