Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Can-Fite BioPharma Licenses Potential Inflammatory Disease Rxs from Leiden U, NIH
Can-Fite will pay Leiden University and NIH an upfront fee and annual minimal royalties; milestone payments until marketing approval; and royalty payments on net sales of future products.
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