Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
VC Bets on European, Asian, Mid-East Life-Sci Shops Shrivel in Q1, Dow Jones Report Shows
"Whether it's in the US, Europe, China, or India, VCs are just focusing on supporting their established portfolio companies rather than taking new risks in new startup companies," a Dow Jones Financial Information Services researcher said.
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