Chromosome-Scale Selective Sweeps and Genomic Diversity in C. elegans
Andersen, Gerke et al., Nature Genetics
Researchers at Princeton University and elsewhere discuss the effects of chromosome-scale selective sweeps on genomic diversity in Caenorhabditis elegans. Taking a high-throughput selective sequencing approach on a collection of 200 wild C. elegans strains, the team found that the nematode's "genome variation is dominated by a set of commonly shared haplotypes on four of its six chromosomes, each spanning many megabases." Further, the team reports on its population genetic modeling experiments, which showed that "this pattern was generated by chromosome-scale selective sweeps that have reduced variation worldwide; at least one of these sweeps probably occurred in the last few hundred years," it writes.
Montgomery County Sets Fall Vote on Gaithersburg West Plan for 8M+ Sq. Ft. of New Life-Sci Space
The county's Planning Board said Thursday it expects the County Council to decide on the so-called Gaithersburg West Master Plan on Sept. 15, which would more than double the county's current inventory of life-sci R&D space.
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