Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
MoneyTree: Nation's Biggest Bioclusters Record Declines in VC Spending in Q2
The San Francisco Bay Area and Boston/Cambridge, Mass., fared better in biotech activity than almost the entire next tier of large life-sci clusters, but worse than several up-and-coming regions, which saw either smaller year-to-year losses, or actual gains.
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