Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Life-Science Sector Records Declines in First-Quarter Venture Capital Funding
Venture capitalists investments declined either 17.4 percent or 59 percent in the first quarter, according to two separate studies, as the sputtering US economy weighed on investors. The contraction also underscores a shift in the types of companies pursuing private equity, the amount of capital they seek, and what they plan to do with the money, several market watchers told BioRegion News.
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