Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Home of Hershey Chocolate Bars Bares Its Sweet Tooth for Life-Science Startups
The 80,448-square-foot Hershey Center for Applied Research, opened two years ago, is the first of up to a dozen buildings totaling 1.2 million square feet envisioned for a 165-acre campus near Penn State's Milton S. Hershey Medical Center.
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