Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
As Georgia Readies for BIO, Its Leaders Hope Meeting Will Raise State's Life-Sci Standing
GeorgiaBio is counting on the Biotechnology Industry Organization's International Convention, which starts Monday, to help the state emerge from the shadow of two Southeastern rivals into a top choice for life-sci companies.
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