Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Deloitte Finds NJ Lost 1,400 Pharma and Med Device Jobs in 2008 Amid Rising Economic Impact
A total 59,948 biopharma and med device jobs were based in the Garden State in 2008, according to a recent report — down more than 2 percent from 61,347 employees a year earlier. However, jobs attributable to indirect economic effects from life science firms rose by almost 7 percent in that time.
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